Assessment of clinical effectiveness of haemoglobin spray as adjunctive therapy in the treatment of sloughy wounds

Sharon D Hunt, Fredrik Elg, Steven L Percival

Journal of Wound Care | Vol. 27 | No. 4 | pp 210–219

Objective: To assess use of an adjunctive topical haemoglobin spray in the treatment of sloughy wounds.

Results: After 26 weeks, 94/100 patients (94%) treated with haemoglobin spray were completely healed compared with 63/100 control patients (63%). Positive results were evident as early as week one with 52% mean wound size reduction using the heamoglobin spray versus 11% in the retrospective control (p<0.001). At baseline, mean slough coverage was higher in the haemoglobin group, 58% versus 44% in the control group (p<0.001). By week four, mean slough coverage was 1% in the haemoglobin versus 29% in the control group (p<0.001). Reductions in exudate and pain levels (p<0.001) were also observed.

Conclusion: Overall, results of this evaluation showed the addition of adjunctive haemoglobin spray to standard wound care treatment achieved positive clinical outcomes for patients self-managing complicated sloughy wounds, by supporting reduction of wound exudate and slough within the complex multifaceted process of wound healing.

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